WHOLE-BODY IMAGING INFECTIOUS DISEASE MODELS

  • Imaging in vivo antiobitic efficacy 
  • GFP or RFP labeling of bacteria of interest
  • Imaging effects of virulence genes in vivo
  • All in vivo infection applications and organs

WHOLE-BODY FLUORESCENT IMAGING OF E-Coli-GFP IN VARIOUS ORGANS AFTER GAVAGE

0 min

10 min

20 min

30 min

120 min

 

WHOLE-BODY FLUORESCENT IMAGING OF Salmonella-GFP IN VARIOUS ORGANS AFTER GAVAGE

0 min

10 min

30 min

70 min

240 min

Zhao, M., Yang, M., Baranov, E., Wang, X., Penman S., Moosa, A.R., and Hoffman, R.M. Spatial-temporal imaging of bacterial infection and antibiotic response in intact animals. Proc. Natl. Acad. Sci. USA 98, 9814-9818, 2001

DUAL COLOR WHOLE-BODY IMAGING OF E-Coli-GFP and Salmonella-GFP INFECTION IN NUDE MOUSE