Subcutaneous tumor models
• Nude mice bred in house
• Well defined tumor lines supplied from our stocks
• Propagation of tumor cells
• Injection of tumor lines into the nude or SCID mice and propagating of sc tumor
• Implantation of tumor fragments or cells into mice
• Dosing routes including iv, ip, im or oral gavage, intratumor, sc.
• Measurement of tumor size , body weight on adaily basis or as described in the protocol
• Plots of growth curves
• Necropsy , tumor weight, harvesting tumors, blood, any organ at the end of the study and slide preparation as required