GeneCeuticals® Publications:
Hasegawa,
S., Yang, M., Chishima, T., Shimada, H., Moossa, A.R., Hoffman, R.M.
In vivo tumor delivery of
the green fluorescent protein gene to report future occurrence of
metastasis. Cancer Gene Therapy 7,
1336-1340, 2000.
Miki,
K., Xu, M., An, Z., Wang, X., Yang, M., Al-Refaie, W., Sun, X., Baranov, E.,
Tan, Y., Chishima, T., Shimada, H., Moossa, A.R., Hoffman, R.M.
Survival efficacy of the combination of the methioninase gene and
methioninase in a lung cancer orthotopic model.
Cancer Gene Therapy 7,
332-338, 2000.
Miki,
K., Al-Refaie, W., Xu, M., Jiang, P., Tan, Y., Bouvet, M., Zhao, M., Gupta,
A., Chishima, T., Shimada, H., Makuuchi, M., Moossa, A.R., and Hoffman, R.M.
Methioninase gene therapy of human cancer cells is synergistic with
recombinant methioninase treatment. Cancer Research 60,
2696-2702, 2000.
Miki,
K, Xu, M., Gupta, A., Ba, Y., Tan, Y., Al-Refaie, W., Bouvet, M., Makuuchi,
M., Moossa, A.R., and Hoffman, R.M. Methioninase
cancer gene therapy with selenomethionine as suicide prodrug substrate.
Cancer Research 61,
6805-6810, 2001. [PDF]
Masako Kamiyama, Yasushi Ichikawa, Takashi Ishikawa, Takashi Chishima, Satoshi Hasegawa, Yohei Hamaguchi, Yoji Nagashima, Yohei Miyagi, Masato Mitsuhashi, David Hyndman, Robert M Hoffman, Shigeo Ohki and Hiroshi Shimada VEGF receptor antisense therapy inhibits angiogenesis and perotoneal dissemination of human gastric cancer in nude mice. Cancer Gene Therapy, 9, 197-201, 2002. [PDF]
Pirocanac, E.C., Nassirpour, R., Yang, M, Wang, J-W., Nardin, S.R., Gu, J., Fang, B., Moossa, A.R., Hoffman, R.M., and Bouvet, M. Bax-induction gene therapy of pancreatic cancer. J.Surg.Res. 106, 346-351, 2002.[PDF]
Hoffman, R.M. Immune reactions in skin and hair follicle gene therapy. Molecular Therapy 7, 294-295, 2003.[PDF]
Katz, M.H., Spivack, D.E., Takimoto, S., Fang, B., Burton, D.W., Moosa, A.R., Hoffman, R.M., and Bouvet, M. Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter. Annals of Surgical Oncology 10, 762-772, 2003.[PDF]
Yamamoto, N., Gupta, A., Xu, M., Miki, K., Tsujimoto, Y., Tsuchiya, H., Tomita, K., Moosa, A.R., and Hoffman, R.M. Methioninase gene therapy with selenomethionine induces apoptosis in bcl-2-overproducing lung cancer cells. Cancer Gene Therapy 10, 445-450, 2003. [PDF]
Gupta, A., Miki, K., Xu, M., Yamamoto, N., Moosa, A.R., and Hoffman, R.M. Combination efficacy of doxorubicin and adenoviral methioninase gene therapy with prodrug selenomethionine. Anticancer Research 23, 1181-1188, 2003.