BREAKING NEWS

Press Release July 12, 2010

AntiCancer, Inc. and Cambridge Research & Instrumentation

Settle Patent Litigation after 3 ½ Years

AntiCancer, Inc., and Cambridge Research & Instrumentation, Inc. (CRi) have agreed to settle patent litigation which has been ongoing between the two companies in the U.S. District Court for the Southern District of California since January 2007. Company presidents Robert M. Hoffman, Ph.D. (of AntiCancer) and George A. Abe (of CRi) announced the agreement today. The settlement resolves all claims between the parties. Financial terms were not disclosed.

AntiCancer, Inc. is a leader in providing animal models, cell lines, and therapeutics for imaging tumor cells in small animals. Its stock is privately held. AntiCancer is headquartered in San Diego, California, where it remains the oldest free-standing biotechnology company in the San Diego cluster. AntiCancer has subsidiaries in China, Japan, and Korea. More information about AntiCancer is available at www.anticancer.com. CRi develops and sells optical imaging systems to advance biomedical research and molecular-based drug and diagnostic development. Its stock is privately held. CRi is headquartered in Woburn, Massachusetts. More information about CRi is available at www.cri-inc.com.

New Gene-Based Fluorescence-Labeling Technology for Cancer Surgery

• News:

• Kishimoto, H., Zhao, M., Hayashi, K., Urata, Y., Tanaka, N., Fujiwara, T., Penman, S., and Hoffman, R.M. In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation. Proc. Natl. Acad. Sci. USA, 1-6, 14514-14517, 2009

• Highlights (please see Medical Sciences):

• Science Magazine Editor’s Choice:

• MIT Technology Review:

Human hair follicle stem cells repair nerves

• News:

• Amoh, Y., Kanoh, M., Niiyama, S., Hamada, Y., Kawahara, K., Sato, Y., Hoffman, R.M., and Katsuoka, K. Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral-nerve injury: An advantageous alternative to ES and iPS cells. J. Cell. Biochem. 107, 1016-1020, 2009

• Scientists extract pluripotent stem cells for medical use from and unexpected source: hair:

• BioWorld Today (July 22, 2009…page 2):

National Cancer Institute (NCI) designates AntiCancer Inc. as a Success Story

Hair follicle stem cells used to repair spinal cord injury

• News:

• Amoh, Y., Li, L., Katsuoka, K., and Hoffman, R.M.  Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function.  Cell Cycle 7, 1865-1869, 2008. 

• Supplemental Movie 1- Before treatment:  

• Supplemental Movie 2- After treatment:  

Caliper and AntiCancer announce cross-licensing of intellectual property and settlement of litigation

Kevin Hrusovsky, President and CEO of Caliper, and Robert Hoffman, Ph.D., President and CEO of AntiCancer