Products and Services


1.  GFP and RFP expressing cell lines

2.  PDX and PDOX mouse models of

     all major cancer types.

3.  RFP, CFP and GFP expressing

     transgenic nude mice

4.  Contract research of any type

     involving mice and rats, including

     PDX and PDOX models,

     syngeneic models, transgenic

     models, aging, diabetes,

     obesity, NASH, multiple sclerosis

     and other disease models.

5.  Histoculture drug response

     (HDRA) 3D explant culture for

     drug discovery and cancer

     patient directed research

     clinically validated by 10 clinical

     trials since 1987!

(See HDRA Publications)

6. AntiCancer's recombinant

    methioninase (rMETase)

    for methionine restriction is more

    effective than low methionine   

    medium or diet:


3D molecular structure of methioninase


Methioninase related videos

by Dr. Hoffman


Please contact AntiCancer at to purchase any quantity of methioninase.

(See Methioninase Publications)


Compare AntiCancer's contract research to any other company

Crown, Champions, Charles River, Covance. AntiCancer is far superior, proven by 1100 publications and led by Dr. Robert Hoffman,

whose 55 years of highly innovative science place him as a world leader.


Only AntiCancer offers orthotopic mouse models of cancer: established by surgical orthotopic implantation (SOI)


GFP-expressing metastasis in an untreated orthotopic nude - mouse model of PC-3 human prostate cancer

Mouse with orthotopic model of GFP-expressing human PC-3 prostate cancer treated with drug X.




Testimonial video of cancer patient whose metastatic tumor was regressed by effective drugs identified by AntiCancer scientists in a PDOX model of the patients tumor.


AntiCancer, Inc. 7917 Ostrow St

 San Diego, CA 92111

Tel: 858-654-2555 

Fax: 858-268-4175



Contact us to set up Zoom meeting!


AntiCancer websites:

Copyright © 2020.
AntiCancer, Inc.
All rights reserved





Please check the following link to access Dr. Hoffman’s webinar:


As a default process, you will have to enter your name and email address to access the recording.


The world's most scientific preclinical cancer CRO! 36 years of service!


STEP UP to AntiCancer's orthotopic models of cancer for accuracy of drug evaluation and discovery demonstrated in more than 500 AntiCancer publications

AntiCancer, Inc. is the world leader in orthotopic cancer models and the only company offering PDOX (orthotopic PDX) models


AntiCancer is open for business to carry out all your mouse experiments.

Nude and Other Mouse Strains Available Now!

SCID, C-57 Black, Balb C at 50% off market price.


World's greatest collection of fluorescent cell lines avaiable!

        -> Drug Discovery              -> Grant Subcontractor
        -> Drug Evaluation              -> Provide PDOX/PDX models


   For accurate drug discovery and evaluation use AntiCancer orthotopic tumor models. All available for contract research:

   All models non-invasively imageable with fluorescent proteins.


   36 years experience with over 700 contracts and 1100 scientific publications.


Stepping up The War on Cancer with New Technology


Learn how Dr Robert Hoffman is shifting the paradigm in cancer research.


1. GFP and RFP cancer cell lines.

2. Nude mice expressing fluorescent proteins.

3. PDOX ® Patient-derived orthotopic xenografts

          A. Letter from The Founder Robert M. Hoffman

          B. New York Times - PDOX Patent

          C. Nature Reviews Cancer PDOX paper by Robert Hoffman

          D. PDOX Trademark

          E. PDOX Book

          F. Bibliography of AntiCancer's PDOX publications

          G. News Release

          H. Law 360

          I. Bibliography of AntiCancer's drug - discovery


        J. Appointment of AntiCancer Founder Robert M Hoffman

            as Honorary Chairman of the Chinese Society of

            Precision Medicine

        K. CV of Robert Hoffman; Have the world's foremost

             authority on orthotopic models of cancer oversee your

             contract research.

        L. The AntiCancer Laboratory of Precision Medicine ( ALPM)

             Dr. Hoffman speaks about precision medicine for cancer.

             (video ) 

        M. Patient-derived Orthotopic (PDOX®) Models Available

              for Purchase

        N. Publications from AntiCancer’s CRO work for Gilead

             Sciences ,

        O. AntiCancer's 35th Anniversary

        P. Photograph of the AntiCancer Team: the world's most

             innovative preclinical cancer CRO.











 Histoculture Drug Response Assay


Ex vivo patient-tumor fragment culture


A.Radioactive nuclei silver grains,

which appear green due to

polarization microscopy indicate dividing cells.



B. Epi-illumination polarization

microscopy without bright-field light highlight dividing cells


Ex vivo tumor fragment culture shows individual cancer response to doxorubicin.


Doxorubicin concentration

Graphic responses of a series of histocultured breast tumors in the



ALERT to Scientists, Doctors and Cancer Patients

There is a company stating  on their website that they perform AntiCancer's PDOX technology calling it "orthotopic PDX", and their own.  This company posts on their website a partial  list of AntiCancer's  PDOX publications stating it is their publications. This company claims on their website 600 studies with their model, which are the studies AntiCancer  has performed in its  more than 35 years in business. This company exhibits AntiCancer's data on its website without attribution to AntiCancer or the journal it was published in. This company has not published a single paper of their own and has  no demonstratable ability to make a PDOX( "orthotopic PDX" ) model. This company touts its tumor bank which they stole from AntiCancer and told the Court it would never allow its inspection by AntiCancer. The stolen tumor bank contains patient tumors immortalized in mice by AntiCancer, carried out under support by a US Government grant which retains certain sharing rights to these immortalized tumors. Thus the main perpetrators to the theft of AntiCancer's tumor bank, this Company's CEO and its "Chief Scientific Officer", also stole Government property. Potential customers of this company should take this into consideration. The CEO brags he sold "his" previous start-up for $190 million; but his role in this company was only a salesman. This company solicits cancer patients stating they can make a PDOX ("orthotopic PDX") model for their tumor, despite having no proof they can do so. This company now claims "certainty" to be able to identify effective drugs with "their" "O-PDX" mouse model without presenting a single publication or even a graph or table of data demonstrating their ability to do what they claim. The company claims a CLIA license to  test drugs in their "orthotopic PDX " model  and recommend that the patient be treated with drugs despite no demonstratable ability to do so.  This can endanger the life of the cancer patient. This company received a CLIA certificate only to evaluate histopathology slides [violation of 42 CFR 493.63(b)]. The director of this company's CLIA laboratory has no demonstratable experience with mouse models of cancer. This company claims "its" orthotopic PDX (O-PDX) for "cancer not responding to meds", will identify "The right cancer treatment, the first time, every time, precision oncology for patients, individualized O-PDX testing can determine the best therapy for your unique cancer". This claim is made with no demonstrated basis of this company's ability to do so. The CEO of this Company said in a sworn declaration to the Court, that patients at a major state University hospital signed a consent form for their surgeon who is Chairman of the company's Scientific Advisory Board, that specifically assigns their tumors to the Company. This appears to be a major conflict of interest and possibly a crime and is reminiscent of a previous scandal where cadaver body parts were sold from a medical school resulting in long prison sentence for the perpetrators. This company's modus operandi appears to be The Big Lie. This company appears to have defrauded investors, doctors and patients. This company's lawyer has been reprimanded by the California Bar for unethical conduct and is a secret shareholder of the company which he did not declare to the Court, and in his apparent dementia fancies himself another "David Boies".  A new Director and head of the "Executive Committee" made hundreds of millions in oil and gas, seems to be funding the burn rate of the Company and serves as the company bully. The Director of this Company who came up with the Big Lie that this Company can provide "Certainty" for the cancer patients, also fancies herself a Broadway Producer. Compare this company and the "Certainty" Director with Theranos (CR 18  C0258) whose principals have been indicted with 11 felony fraud counts in Federal Court.

ALERT to Pharma and Biotech

Companies advertising ex vivo PDX explant or fragment culture for drug evaluation are selling technology misappropriated from AntiCancer